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The Black Stars defeated DR Congo by 2-1 in the quarter-finals, whiles Cameroon defeated pre-tournament favourites Senegal 5-4 on penalties to advance.
Both sides will meet on Thursday to decide who makes it into the final to face either Egypt or Burkina Faso, who will go head-to-head in the other semi-final clash.
Atsu, who has been very influential in Ghana's campaign so far, insists the Black Stars will leave no stone unturned when they meet the Indomitble Lions.
"We are in the semi-finals. We are going to relax and prepare for the Cameroon test,'' Atsu told a media conference.
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"I cannot predict football. I just hope that we get to the final in the end.
"We are meeting Cameroon in semi-finals so we will check and see their weaknesses and work towards that."
Ghana made it to the final in 2015 and will be looking to repeat that feat when they face Cameroon on Thursday.