The suspect, Rachel Tetteh was picked up after she allegedly beheaded her husband who was found in a pool of blood on a farm footpath with a severed head.
The headless body has been deposited at the New Tafo Akim Government Hospital morgue for preservation and autopsy.
It's unclear what triggered the suspect to commit such a heinous crime.
The police said "The suspect has since been arrested and the cutlass with which she allegedly butchered the deceased is being kept for evidence.
"The case is under investigation. Any further developments will be communicated."