Thomas Partey, known for his exceptional skills and contributions to both the national team and his club, Arsenal, will not be part of the squad representing Ghana in the AFCON Cote d'Ivoire 2023.
The absence of the midfielder, who has been a key figure in previous national team campaigns, adds an unexpected twist to Ghana's lineup.
Partey has been sidelined from competitive action since Ghana's October friendly matches against Mexico and the United States of America.
The Arsenal midfielder resumed team training only last month after recovering from his October injury, but Hughton has decided to exclude him.
Lamptey is another casualty who will not feature in the tournament due to injury despite the right-back's initial inclusion in the provisional squad sparking questions, he will now be absent from the continental competition.
While Thomas Partey's absence is undoubtedly a significant talking point, the AFCON Cote d'Ivoire 2023 squad is filled with a mix of experienced players and emerging talents poised to make an impact.
Three players from the Ghana Premier League cut Hughton's 27-man squad, including Richmond Lamptey from Asante Kotoko, Hamid Abdul Fatawu, and Jonathan Sowah from Medeama, both earning their first call-ups to the Black Stars.