Both the novel and the show are set in the fictional New England town of Three Rivers, Connecticut, and the location often acts like another character on screen, and the in-town diner, creepy forensic hospital, and Thomas' home are all important parts of the story. However, fans are curious to know if the show really filmed in Connecticut.

Where is I Know This Much Is True filmed?

I Know This Much Is True was filmed in New York State in the cities of Poughkeepsie, Wappingers Falls, and Kingston. Filming also took place at the Umbra of Newburgh soundstage in New York.

In Poughkeepsie, locations like the Vassar Brothers Medical Centre, Vassar College, Seasons Fishkill Restaurant, 9 Mall Plaza, and All Sports Health and Fitness were used for various scenes.

According to Cinemaholic , Lamb wanted the show to be filmed in Eastern Connecticut, and he took Ruffalo and director Derek Cianfrance on a tour of various locations in Mansfield, where he currently lives. While production ultimately settled on New York for filming, Lamb ultimately felt that the locale still gave the show the tone he wanted.