The Nuhu twin brothers captured the headlines as they scored both goals for Ashanti Gold in their debut league game for the league champions.
Alhassan Fuseini shot Ashanti Gold into the lead before Bernard Ofori, the player who scored the only goal in the Super Cup, once again scored against the home side from the spot kick to give Medeama the equalizer before the half time break.
However, just about three minutes from the first half break Fuseini Nuhu, the top scorer for New Edubiase last season snatched the match winner for the champions to earn them an important victory.
Ashgold per the win have maintained their unbeaten home recxord on match day 1, since their debut appearance in the 1985-86 season.
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Last Season Medeama lost at Obuasi by the same margin.