Opoku Ware School suffered a defeat to debutants Sonrise SHS from Ho in the Volta region in a nail-biting contest.
Whilst the results are utterly shocking, all hope is not lost for two-time NSMQ champions OWASS, as their points are high enough to ensure their qualification to the next stage of the competition as one of the 18 highest-scoring losing schools.
READ MORE: Konongo-Odumase SHS records highest scores at NSMQ2018 Prelims
In 2017, Opoku Ware School was eliminated at the 1/8 stage of the competition by Keta SHTS.
Prior to making their first appearance at the National Science & Maths Quiz and Science Festival, Sonrise SHS won their Volta Regional contest against St. Paul's SHS, Nkwanta Community SHS and Kete Kratchi SHS.